Multiple Organ Failure Pathophysiology and Potential Future Therapy

Pathophysiology, monitoring, and therapy of shock with organ failure

Half of the two million persons in the United States who die annually die acutely of circulatory problems, shock and its sequelae, organ failure. Since shock is the commonest complication of high risk surgery, trauma, and acute illnesses, its early recognition and correction are key to its prevention. Thus, it is extremely important to recognize shock as early as possible and to vigorously trea...

Nutrition and Multiple Organ Failure

Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome.

OBJECTIVE To describe the pathophysiology associated with multiple organ dysfunction syndrome in children. DATA SOURCES Literature review, research data, and expert opinion. STUDY SELECTION Not applicable. DATA EXTRACTION Moderated by an experienced expert from the field, pathophysiologic processes associated with multiple organ dysfunction syndrome in children were described, discussed, ...

Burn shock and multiple organ failure syndromes

Critical condition, developing in patients with burns during the burn shock more often produce the development of nonspecific reactions in the body, manifested as the system or the organ insufficiency and are determined by the term «syndrome of poly organ insufficiency» (SPOI). The course and treatment of 189 patients with burn shock have been analyzed. With the purpose of investigation all pat...

Pediatric septic shock and multiple organ failure.

In the last 5 years, the understanding of the epidemiology and pathogenesis of pediatric sepsis, septic shock, and multiple organ failure has expanded greatly. There has also been a substantial increase in the number of successful randomized trials in which success has been measured as reduction in mortality in adults, children, and newborns. This article discusses these advances, updating the ...